畢尼(Binesh Unnikrishnan) 助理教授

專長：海洋源生物分子、碳量子點與奈米生物技術於神經退化性疾病及癌症之藥物開發與傳遞研究

電子郵件：Binesh@mail.ntou.edu.tw

學歷：國立臺北科技大學能源與光電材料博士

研究室：

發表論文

1. Anisha Anand^†, Binesh Unnikrishnan^†, Chen-Yow Wang, Jui-Yang Lai, Han-Jia Lin, Chih-Ching Huang, Phosphate ester-linked carbonized polymer nanosheets to limit microbiological contamination in aquaculture water, npj Clean Water, 2024, 7. Article no. 84. †Equal Contribution
2. Yu Tang, Binesh Unnikrishnan, Ju-Yi Mao, Chin-Jung Lin, Chen-Yu Lee, Chen-You Wang, Cheng-Yen Li, Han-Jia Lin, C. Perry Chou, Chih-Ching Huang, Edge-State Programmed Carbonized Nanogels Enable Precise Hot-Start PCR by Multivalent Enzyme Inhibition, Small, 2026, e12777.
3. Binesh Unnikrishnan, Jui-Yang Lai, Anisha Anand, Chih-Ching Huang, Huan-Tsung Chang, Tiny tools, big vision: A minireview on carbonized nanomaterials in ophthalmology, Journal of Controlled Release, 2025, 388, 114396.
4. Saumyadip Sarkar, Chen-Yow Wang, Pang-Hung Hsu, Binesh Unnikrishnan, Yu Tang, Shiow-Yi Chen, Chin-Jung Lin, Anisha Anand, Ren-Hong Shih, Li Er Hean, Pin-Yuan Chen, Ruo-Yi Huang, C Perry Chou, Chih-Ching Huang, In situ incorporation of boronate into carbonized alginate nanogels for targeted inhibition of triple-negative breast cancer metastasis by inducing cytoskeletal disruption, cell growth arrest, and apoptosis. Biomaterials, 2026, 324, 123500.
5. Binesh Unnikrishnan, Anisha Anand, Chin-Jung Lin, Chen-Yu Lee, Amit Nain, Pavitra Srivastava, Ren-Siang Wu, Han-Wei Chu, Chen-Yow Wang, Ren-Hong Shi, Kuan-Hung Lee, Jin-Xuan Chen, Jyoti Shanker Pandey, Jui-Yang Lai, Chih-Ching Huang, Huan-Tsung Chang, Exploring cellular dynamics: Engineered fluorescent carbon dots for organelle staining and cellular response analysis, Coordination Chemistry Reviews, 2025, 534, 216552.
6. Arumugam Sangili^†, Binesh Unnikrishnan^†, Shun Ruei Hu, Han-Wei Chu, Hung-Lung Chou, Ren-Siang Wu, Chih-Ching Huang, Huan-Tsung Chang, Ammonia-assisted heterocyclic amine exerts soft delamination and interlayer engineering of Ti₃C₂T_x MXene for fabricating stable supercapacitors, Energy Storage Materials, 2024, 73, 103809. †Equal Contribution
7. Anisha Anand, Chih-Ching Huang, Jui-Yang Lai, Darakhshan Bano, Helen Indah Pardede, Amina Hussain, Sehresh Saleem, Binesh Unnikrishnan*, Fluorescent carbon dots for labeling of bacteria: mechanism and prospects—a review, Analytical and Bioanalytical Chemistry, 2024, 416, 3907–3921.  *Corresponding Author
8. Han-Wei Chu, Wan-Jyun Chen, Ko-Hsin Liu, Ju-Yi Mao, Scott G Harroun, Binesh Unnikrishnan, Han-Jia Lin, Yunn-Hwa Ma, Huan-Tsung Chang, Chih-Ching Huang, Carbonization of quercetin into nanogels: A leap in anticoagulant development, Journal of Materials Chemistry B, 2024, 12, 5391-5404.
9. Hong-Jyuan Jian, Anisha Anand, Jui-Yang Lai, Binesh Unnikrishnan, Huan-Tsung Chang, Scott G Harroun, Chih-Ching Huang, In Situ Hybridization of Polymeric Curcumin to Arginine-Derived Carbon Quantum Dots for Synergistic Treatment of Bacterial Infections, ACS Applied Materials & Interfaces, 2023, 15, 22, 26457–26471.
10. Cheng-Ruei Yang, Yu-Syuan Lin, Ren-Siang Wu, Chin-Jung Lin, Han-Wei Chu, Chih-Ching Huang, Anisha Anand, Binesh Unnikrishnan, Huan-Tsung Chang, Dual-emissive carbonized polymer dots for the ratiometric fluorescence imaging of singlet oxygen in living cells, Journal of Colloid and Interface Science 2023, 634, 575–585.
11. Binesh Unnikrishnan^†, Chien-Wei Wu^†, Arumugam Sangili, Ya-Ju Hsu, Yu-Ting Tseng, Jyoti Shanker Pandey, Huan-Tsung Chang, Chih-Ching Huang, Synthesis and in situ sulfidation of molybdenum carbide MXene using fluorine-free etchant for electrocatalytic hydrogen evolution reactions, Journal of Colloid and Interface Science 2022, 628, 849-857. †Equal Contribution
12. Arumugam Sangili, Binesh Unnikrishnan, Amit Nain, Ya-Ju Hsu, Ren-Siang Wu, Chih-Ching Huang, Huan-Tsung Chang, Stable carbon encapsulated titanium carbide MXene aqueous ink for fabricating high-performance supercapacitors, Energy Storage Materials, 2022, 53, 51-61.
13. Han-Wei Chu, Binesh Unnikrishnan, Amit Nain, Scott G. Harroun, Huan-Tsung Chang, Chih-Ching Huang, Pulsed laser irradiation induces the generation of alloy cluster ions for the screening of protease activity, Biosensors and Bioelectronics 2022, 216, 114615.
14. Anisha Anand, Binesh Unnikrishnan, Ju-Yi Mao, Chin-Jung Lin, Jui-Yang Lai, Chih-Ching Huang, Carbon-based low-pressure filtration membrane for the dynamic disruption of bacteria from contaminated water, Water Research 2022, 212, 118121.
15. Chin-Jung Lin, Binesh Unnikrishnan, Caitlin W. Lehman, Pei-Hua Wang, Yufeng Jane Tseng, Scott G. Harroun, Shih-Chao Lin, Chih-Ching Huang, Exploring molecular moieties on carbonized polymer dots from flavonoid glycosides with activity against enterovirus A71, Carbon 2022, 192, 285–294.
16. Ren-Siang Wu, Yu-Syuan Lin, Amit Nain, Binesh Unnikrishnan, Yu-Feng Lin, Cheng-Ruei Yang, Tzu-Heng Chen, Yu-Fen Huang, Chih-Ching Huang, Huan-Tsung Chang, Evaluation of chemotherapeutic response in living cells using subcellular organelle‒selective amphipathic carbon dots, Biosensors and Bioelectronics 2022, 211, 114362.
17. Yi-Ru Chiou, Chin-Jung Lin, Scott G. Harroun, Yi-Ru Chen, Lung Chang, An-Tai Wu, Fu-Chieh Chang, Yang-Wei Lin, Han-Jia Lin, Anisha Anand, Binesh Unnikrishnan, Amit Nain and Chih-Ching Huang, Aminoglycoside-mimicking carbonized polymer dots for bacteremia treatment. Nanoscale 2022, 14, 11719–11730.
18. Ju-Yi Mao, Dragan Miscevic, Binesh Unnikrishnan, Han-Wei Chu, C. Perry Chou, Lung Chang, Han-Jia Lin, Chih-Ching Huang, Carbon nanogels exert multipronged attack on resistant bacteria and strongly constrain resistance evolution, Journal of Colloid and Interface Science 2022, 608, 813–1826.
19. Wei-Jan Lin, Yu-Syuan Lin, Huan-Tsung Chang, Binesh Unnikrishnan, Chih-Ching Huang, Electrocatalytic CuBr@CuO nanoparticles based salivary glucose probes, Biosensors and Bioelectronics 2021, 194, 113610.
20. Binesh Unnikrishnan^†, Irma Suryani Gultom^†, Yu-Ting Tseng, Huan-Tsung Chang, Chih-Ching Huang, Controlling morphology evolution of titanium oxide–gold nanourchin for photocatalytic degradation of dyes and photoinactivation of bacteria in the infected wound, Journal of Colloid and Interface Science, 2021, 598, 260-273. †Equal Contribution
21. Li-Jyuan Luo, Hong-Jyuan Jian, Scott G. Harroun, Jui-Yang Lai, Binesh Unnikrishnan, and Chih-Ching Huang, Targeting nanocomposites with anti-oxidative/inflammatory/angiogenic activities for synergistically alleviating macular degeneration, Applied Materials Today 2021, 24, 101156.
22. Binesh Unnikrishnan, Chia-Wen Lien, Han-Wei Chu, Chih-Ching Huang, A Review on Metal Nanozyme-Based Sensing of Heavy Metal Ions: Challenges and Future Perspectives, Journal of Hazardous Materials 2021, 401, 123397.
23. Ju-Yi Mao, Binesh Unnikrishnan, Han-Wei Chu, Scott G Harroun, Yet-Ran Chen, An-Tai Wu, Huan-Tsung Chang, Han-Jia Lin and Chih-Ching Huang, Thermally driven formation of polyphenolic carbonized nanogels with high anticoagulation activity from polysaccharides, Biomaterials Science 2021, 9, 4679–4690.